Best Medicine

2026

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Best Medicine

6.7 | en | Drama

Martin Best is a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin's blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he's all they’ve got.

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Seasons & Episodes

EP2 Episode 2

Sep. 22,2026

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EP1 Be Careful What You Fish For

Sep. 20,2026

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While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town. Meanwhile, Judith, a well-meaning townsperson (guest star Andrea Martin), creates havoc while on prescribed oxygen, Louisa continues to see Martin's girlfriend Eden for medical guidance and Greg and George's success from the seas urchin boom take its toll on the both of them.

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6.7 | en | Drama , Comedy

Synopsis

Cast

Josh Charles , Abigail Spencer , Josh Segarra

Director

Producted By

Propagate Content , FOX Entertainment Studios

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Trailers

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Cast

Josh Charles

as Dr. Martin Best

[2026] Best Medicine [2024] Mothers' Instinct [2024] Memory [2024] The Veil [2023] The Power [2022] We Own This City [2022] Facing Suicide [2019] Framing John DeLorean [2018] Amateur

Abigail Spencer

as Louisa Glasson

[2026] Clean Hands [2026] Best Medicine [2023] Extended Family [2021] Rebel [2019] Reprisal [2018] Buttons [2017] The Sweet Life [2017] Three Women [2016] Timeless

Josh Segarra

as Sheriff Mark Mylow

[2026] Roommates [2026] Best Medicine [2025] Friendship [2025] The Threesome [2025] Sirens [2023] Scream VI [2023] The Big Door Prize [2022] She-Hulk: Attorney at Law [2022] Marvel Studios Assembled: The Making of She-Hulk: Attorney at Law